Title: IN VITRO CYTOTOXICITY AND ANTI-INFLAMMATORY ACTIVITY OF YELLOW FLOWERS OF TECOMA STANS L.
Author(s): Sandeep B.Patil, Rutuja M. Sabne, Vijay S. Sawant and Nilofar S. Naikwade
Tecoma stans (L.) Juss. (Yellow bells plants) of the Bignoniaceae family, is an important medicinal plant. It is ornamental surub with 2 to 4 meters hight. It is an important medicinal herb found as a weed throughout India. All parts like seeds, roots and bark are used medicinally. This plants has more medicinal compound constituents are phytosterols, alkaloids, quinines, Also used to cure anti-diabetic, diuretic, anti- spamodic, antimicrobial, anti-fungal and anticancer. The extract was prepared by different process like aqueous, decoction, microwave oven and methanolic maceration and activity was performed by cytotoxicity activity by using brine shrimp lethality assay and anti-inflammatory activity by Egg albumin method. The extracts of yellow flower showed moderate cytotoxicity against brine shrimp (LC50 285.71 μg/mL). The results showed that Methanol Extract of Tecoma stans (L.) Juss are at a concentration of 500 μg/ml significantly protects the heat induced protein denaturation as compared with other forms of extracts.These findings provide scientific evidence to support traditional medicinal uses of T. stans and indicate a promising potential for the development of an Anti-inflammatroy and cytotoxicity agent from T. stans trees.
Keywords: Anti-inflammatroy, Cytotoxicity, brine shrimp lethality assay, Egg albumin method