Title: RECENT ADVANCEMENT IN THE FIELD OF ORPHAN DRUGS – A REVIEW
Author(s): Madhvi Ghadge, Dipayan Purakayastha, Anup Pramanik, Tuman P Rai and Dr.Shiv Garg
Orphan drugs are the pharmaceutical agents that are being used for the treatment, prevention or diagnosis of rare diseases/condition. The incidence of such diseases has been increasing from the last three decades, which led to the need for developing orphan drugs in pharmaceutical industries. The orphan drug act was passed on 28 January, 1983 under National Organization for Rare Diseases. One of the major drawbacks in the field of orphan drug is that the pharmaceutical industry is not very keen to carry-out research on development of orphan drugs as they do not provide a vast profit to the companies. However, in this review; we have discussed the need, drawback, recent development and future prospective for orphan drugs.
Keywords: orphan drugs, neglected diseases, approved drugs, orphan vaccines.